Theranostic nanosystems for targeted cancer therapy
نویسندگان
چکیده
منابع مشابه
An activatable theranostic for targeted cancer therapy and imaging.
A new theranostic strategy is described. It is based on the use of an "all in one" prodrug, namely the biotinylated piperazine-rhodol conjugate 4 a. This conjugate, which incorporates the anticancer drug SN-38, undergoes self-immolative cleavage when exposed to biological thiols. This leads to the tumor-targeted release of the active SN-38 payload along with fluorophore 1 a. This release is mad...
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ژورنال
عنوان ژورنال: Nano Today
سال: 2018
ISSN: 1748-0132
DOI: 10.1016/j.nantod.2018.11.001